Intra Cytplasmic Morphologically Sperm Injection (IMSI)

IMSI – Intra Cytplasmic Morphologically selected Sperm Injection (IMSI)

IMSI – a time tested method and one of the trusted procedures in assisted reproduction processes.

IMSI was first done in 2001, Intracytoplasmic Morphologically Selected sperm Injection (IMSI) is a advanced method of ICSI in which, before the injection procedure, the sperm for the use of IMSI will be selected at improved magnification, which helps, the sperm can be valued for its close nit formation of its inner core and the injection of a regular sperm with a vacuole-free head is fully ensured.

Many researches so far have identified that IMSI is giving a higher result on Pregnancy and Successful delivery, and a very low miscarriage numbers reported.

IMSI is a process involves higher time in completing the whole procedure. But IMSI will be the best procedure to take up after failure in IVF/ ICSI.This procedure will be helpful in getting a higher quality embryo and higher blastocysts. This will be of help for more embryo transfers. IMSI gives a higher success rate than any other procedures, 50% on implantation and an increase of 60% in pregnancy rates.


IMSI will be a beneficial alternative for patients having teratozoospermia. Incase of any regular spermatozoa found with MSOME, the available option will be to go for morphologically tested second-best ones. We have to understand that higher deliveries have been achieved with the use of morphologically amorphous spermatozoa.

For a next option to a failed ICSI, the patients’ selected IMSI procedures were having higher pregnancy level and delivery rates. Its been tested and proved that the IMSI procedure is a the next best option for couples with a first failed ICSI. In case of severe male factor issue patients, the test results gives a increased clinical pregnancy rate with IMSI procedure.